The actress was wearing a simple white blouse with blue jeans and heels as she walked into the clinic. Perhaps she didn't want to be recognized as she also added sunglasses to her outfit.

Melanie Griffith leaves a tattoo removal clinic (FameFlyNet)
This comes shortly after the couple announced their split earlier this month, after being married for almost 20 years.
"We have thoughtfully and consensually decided to finalize our almost twenty years marriage in a loving and friendly manner honoring and respecting each other, our family and friends and the beautiful time we have spent together - Melanie & Antonio," they stated.

Melanie at the reception desk (FameFlyNet)
The tattoo in question is a heart on her arm that had "Antonio" written inside of it. Prior to her appointment on Friday, she had already seemed intent on removing part of the tattoo.
When she attended the Taormina Film Festival recently, the "Antonio" was already missing from inside of the heart.

The clinic specializes in tattoo removal (FameFlyNet)